Tricyclo[3.3.1.1(3,7)]decane-1,3-dicarboxamide

Tricyclo[3.3.1.1(3,7)]decane-1,3-dicarboxamide - Names and Identifiers

Name	Adamantane-1,3-dicarboxamide
Synonyms	Adamantane-1,3-dicarboxamide tricyclo[3.3.1.13,7]decane-1,3-dicarboxamide Tricyclo[3.3.1.1(3,7)]decane-1,3-dicarboxamide
CAS	62472-39-3
InChI	InChI=1S/C12H18N2O2/c13-9(15)11-2-7-1-8(4-11)5-12(3-7,6-11)10(14)16/h7-8H,1-6H2,(H2,13,15)(H2,14,16)

Tricyclo[3.3.1.1(3,7)]decane-1,3-dicarboxamide - Physico-chemical Properties

Molecular Formula	C12H18N2O2
Molar Mass	222.28
Density	1.340±0.06 g/cm3 (20 ºC 760 Torr)
Melting Point	255℃ (cyclohexane )
Boling Point	497.8±15.0 °C(Predicted)
pKa	16.40±0.40(Predicted)
Storage Condition	2-8°C

Tricyclo[3.3.1.1(3,7)]decane-1,3-dicarboxamide - Introduction

Adamantane-1,3-dicarboxamide is an organic compound with the chemical formula C12H16N2O2. It has the morphology of a white crystalline powder.

Adamantane-1,3-dicarboxamide has the following properties:
1. The melting point is high, about 235-238°C.
2. It is stable at room temperature and insoluble in water, but soluble in organic solvents such as methanol, ethanol and ester solvents.
3. It is a colorless or light yellow solid that can be decomposed at higher temperatures.

Adamantane-1,3-dicarboxamide uses include:
1. As a synthetic drug intermediate: Adamantane-1,3-dicarboxamide can be used to synthesize other organic compounds, such as anti-cancer drugs, antiretroviral drugs, etc.
2. As a polymer additive: It can also be used as a polymer additive, thereby changing the properties of the polymer.

There are two main methods for preparing Adamantane-1,3-dicarboxamide:
1. Acylation reaction using adamantane: using adamantane as raw material, it is converted into Adamantane-1,3-dicarboxamide through acylation reaction.
2. Amination reaction using adamantane: Amination reaction is carried out using adamantane as raw material in the presence of amine to obtain Adamantane-1,3-dicarboxamide.

Regarding the safety of Adamantane-1,3-dicarboxamide, no specific safety data is currently available. In general, however, routine safety precautions, such as wearing protective gloves, glasses and laboratory coats, should be taken during operation. Avoid contact with strong oxidants and strong acids during use and storage. If necessary, operate in a well-ventilated area and avoid inhaling dust. If contact occurs, rinse immediately with plenty of water and seek medical help.

Last Update：2024-04-09 21:54:55